Central Asia has endured three decades of multiple transitions.The political life of these post-Soviet states has witnessed an active phase of education and reform of the main vectors of development.The most important international actor that has supported and encouraged this process has been the European Union.From the outset, it must be stated th
Novel strategy for oncogenic alteration-induced lipid metabolism reprogramming in pancreatic cancer
The pathogenesis of pancreatic cancer involves substantial metabolic reprogramming, resulting in abnormal proliferation of tumor cells.This tumorigenic reprogramming is often driven by genetic mutations, such as activating mutations of the KRAS oncogene and inactivating or deletions of the tumor suppressor genes SMAD4, CDKN2A, and TP53, which play
Theoretical and numerical analysis of reinforced concrete beams with confinement reinforcement
This paper discusses the use of confinement in over-reinforced concrete beams.This reinforcement consists of square stirrups, placed in the compression zone of the beam cross-section, in order to improve its ductility.A parametric numerical study is initially performed, using a finite Fossils element computational program that considers the materia
Spot diagnosis: An ominous rash in a newborn
Abstract Purpura fulminans (PF) is an ominous cutaneous condition usually associated with meningococcemia.PF in the newborn is rarely reported.We report the case of a female preterm infant with extensive PF due to group B streptococcus (GBS) septicemia.She developed multi-organ system Accessories failure despite neonatal intensive care support and
A quality evaluation method for the unstructured defect record of relay protection devices based on ontology and knowledge graph
The original unstructured record data for the defect of the relay protection devices (RPDs) may contain problems influencing the data mining, and it is lack of quantitative evaluation.So the purpose of this paper is to evaluate the quality of these defective texts of relay protection devices, and it proposes a text quality evaluation method for the